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Expression data of HNSCC cell lines in normoxia and hypoxia

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE182734
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Hypoxia has been linked to increased treatment resistance in many solid tumors, including head and neck squamous cell carcinoma (HNSCC). We aim to identify genes involved in hypoxia-mediated response to radiotherapy in HNSCC. We used microarrays to investigate the influence of hypoxia on the global gene expression in HNSCC. HNSCC cells ( LK0858, LK0863, UT-SCC-14) were grown in normoxic (21% O2) and hypoxic (1% O2) conditions and thereafter were selected for RNA extraction and hybridization on Affymetrix microarrays.
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2021-08-28
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