Mutagenesis and toxicity assessment and its data set in fresh water fish.

With rapid industrialization, urbanization and changing agricultural practices, various toxic chemicals and pollutants are discharged into various water bodies., exposing many non target aquatic organisms including fish.
Arsenic trioxide is one such toxic chemical which has been extensively studied for its mutagenic, clastogeic, teratogenic, and clastogenic effects( beattie et all,1990, Leonard 1979) in various mammalian model, but is less explored in fish model.( manna and sadhukhan, 1986) .
However in recent years emphasis is being given on exploring various agents which can reduce or minimize cytogenic effects produced by such chemical mutagens.
Vitamin c has already been tested and repeated as an excellent clastogenic(gebhartet al1985, Bose and sinha,1991), , antimutagenic, (shamberger,1984) .
Similarly effects of , and its antigenic property has not been much studied in any fish model as such.

伴随着工业化的迅速推进、城市化进程的加快以及农业实践方式的转变，各种有毒化学品和污染物被排放至不同的水体之中，从而暴露了许多非目标水生生物，包括鱼类。三氧化二砷便是此类有毒化学品之一，其突变原性、断裂原性、致畸性和断裂原性效应（Beattie 等人，1990；Leonard，1979）已在多种哺乳动物模型中得到广泛研究，但在鱼类模型中的研究却相对较少（Manna 和 Sadhukhan，1986）。然而，近年来，人们开始重视探索各种能够减少或最小化此类化学诱变剂产生的细胞遗传学效应的剂型。维生素C已被证实并反复测试为一种优秀的断裂原性（Gebhart 等人，1985；Bose 和 Sinha，1991）、抗诱变剂（Shamberger，1984）。同样，其抗氧化性和抗原性在鱼类模型中的研究也鲜有涉及。