five

Kcna5

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rgd.mcw.edu2025-01-21 收录
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https://rgd.mcw.edu/rgdweb/report/gene/main.html?id=2953
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资源简介:
ENCODES a protein that exhibits delayed rectifier potassium channel activity; outward rectifier potassium channel activity; signaling receptor binding; INVOLVED IN negative regulation of cytosolic calcium ion concentration; positive regulation of G1/S transition of mitotic cell cycle; positive regulation of myoblast proliferation; PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; ASSOCIATED WITH Experimental Autoimmune Myocarditis; Experimental Diabetes Mellitus; hypertension; FOUND IN intercalated disc; intracellular canaliculus; perinuclear region of cytoplasm; INTERACTS WITH (5Z,8Z,11Z,13E)-15-HETE; 1-naphthyl isothiocyanate; allethrin

编码一种展现延迟整流钾通道活性、外向整流钾通道活性、信号受体结合功能的蛋白质;参与细胞质内钙离子浓度负调控、有丝分裂细胞周期 G1/S 期转换的正调控、肌母细胞增殖的正调控;参与阿替洛尔药效学途径、肾上腺素能 β 受体激动剂和 β 受体阻滞剂药效学途径、胺碘酮药效学途径;与实验性自身免疫性心肌炎、实验性糖尿病、高血压相关;存在于肌间线粒体、细胞内管道、细胞核周围质区;与(5Z,8Z,11Z,13E)-15-己烯四烯酸、1-萘基异硫氰酸、除虫菊素相互作用。
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