Factor XIa in Complex with Compound 2d
收藏Protein Data Bank Japan2024-10-16 更新2026-03-28 收录
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Factor XIa in Complex with Compound 2d Descriptor: CITRIC ACID, Coagulation factor XIa light chain, methyl ~{N}-[4-[1-[(1~{R})-1-[5-[3-chloranyl-2-fluoranyl-6-(1,2,3,4-tetrazol-1-yl)phenyl]-1-oxidanyl-pyridin-2-yl]-2-cyclopropyl-ethyl]pyrazol-4-yl]phenyl]carbamate Authors: Shaffer, P.L, Spurlino, J, Milligan, C.M. Deposit date: 2022-05-11 Release date: 2022-08-03 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (1.798 Å) Cite: Discovery of Potent and Orally Bioavailable Pyridine N-Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions. J.Med.Chem., 65, 2022
创建时间：
2022-05-11
