Introduction: Gliomatosis cerebri (GC) is defined by diffuse, widespread glial tumor growth affecting three or more cerebral lobes. Previous studies in gliomas found no distinct histological or molecu
RATIONALE: Drugs used in chemotherapy use different ways to stop cancer cells from dividing so they stop growing or die. PURPOSE: Phase I trial to study the effectiveness of VNP40101M in treating pati
Aggressive metastatic cancer remains a major clinical challenge due to the unclear underlying mechanisms and the limited treatment options available. N6-methyladenosine (m6A) is a reversible modificat