Intestinal Dysbiosis and Biotin Deprivation Induce Alopecia through Overgrowth of Lactobacillus murinus in Mice. Ligilactobacillus murinus strain:KM-1

We demonstrated that the gut microbiota play a role in the pathogenesis of alopecia. Gut dysbiosis, especially the overgrowth of L.murinus, and subsequent biotin deficiency are critical steps that lead to the development of alopecia. The gut microbiota and its metabolism are potential targets for the management of skin diseases with impaired hair physiology.