A summary of the dynamic analysis results of the T-LGL survival signaling network.

The first two columns from the left list the components of the network (except for the six source nodes) and their T-LGL states. The nodes' states marked with a * symbol were not documented experimentally in T-LGL before and were predicted by our steady state analysis. The references for the nodes' states documented before are given in the third column. The fixed point(s) obtained after each of the nodes' states is reversed is given in the fourth column, while the size of the exclusive basin of attraction of the normal fixed point, expressed as a percentage of the whole relevant state space, is indicated in the fifth column. The reference of the perturbation cases for which experimental evidence exists is given in the last column. The first 19 nodes in the first column are potential therapeutic targets for T-LGL leukemia.1Evidence in NK-LGL leukemia.