Treatment of prostate cancer cell lines DU-145 and LNCaP with zebularine

ChEBI2013-10-24 更新2026-07-21 收录

癌症表观遗传治疗

DNA甲基化抑制剂实验

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-51629 数据链接链接失效反馈

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Treatment of prostate cancer cell lines DU-145 and LNCaP with zebularine

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2013-10-24

Epigenetic therapies in ovarian cancer alter repetitive element expression in a TP53-dependent manner: TykNu Tiplicate RNA-seq

癌症表观遗传治疗

重复元件转录调控

Abstract: Epithelial ovarian carcinomas (OC) are particularly deadly due to intratumoral heterogeneity, resistance to standard-of-care therapies, and poor response to alternative treatments such as im

NIAID Data Ecosystem70

Effects of SGI-110 on A2780 ovarian cancer xenografts

癌症表观遗传治疗

DNA甲基化药物反应

Genome-wide DNA methylation profiles of SGI-110-treated ovarian cancer xenografts were obtained using next generation Illumina Infinium 450k assay which includes over 450,000 GpG sites. DNA from 6 sam

NIAID Data Ecosystem40

YM155 in combination with EZH2 inhibiton induces synthetic lethality

合成致死药物

癌症表观遗传治疗

EZH2 inhibitors have been developed to treat certain cancers. To maximize the anticancer acttivity of EZH2 inhibition, we combined an EZH2 inhibitor EPZ6438 with YM155, which leads to dramatic cell de

NIAID Data Ecosystem30

Additional file 7 of Combined inhibition of histone deacetylase and cytidine deaminase improves epigenetic potency of decitabine in colorectal adenocarcinomas

癌症表观遗传治疗

表观遗传药物响应

Additional file 7. Table S5.1. CpG islands information in promoters of decitabine responsive genes. Table S5.2. CpG islands information in promoters of decitabine and PBA responsive genes.

NIAID Data Ecosystem40

SMARCA4 Phosphorilation inhibition

癌症表观遗传治疗

激酶抑制剂开发

Cyclin-Dependent Kinase 9 (CDK9) as part of the PTEFb complex promotes transcriptional elongation and high-level gene expression. We now report that, paradoxically, CDK9 is also essential for maintain

NIAID Data Ecosystem30

Treatment of prostate cancer cell lines DU-145 and LNCaP with zebularine

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