fecal 16S rRNA_vancomycin

To investigate the potential roles of gram-positive and gram-negative gut bacteria on the response to IR, mice received oral vancomycin or gentamicin three weeks prior to tumor inoculation, and for the duration of the experiment. Mice receiving vancomycin exhibited increased tumor growth delay following IR as compared to gentamicin-treated or control animals. Ten days post vancomycin administration, fecal samples of vancomycin-treated and control mice were collected for 16S rRNA sequencing.