HeparinaseII H202A/Y257A double mutant complexed with a heparan sulfate tetrasaccharide substrate

HeparinaseII H202A/Y257A double mutant complexed with a heparan sulfate tetrasaccharide substrate Descriptor: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Heparinase II protein, ... Authors: Shaya, D, Cygler, M. Deposit date: 2008-08-18 Release date: 2008-12-30 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate. J.Biol.Chem., 285, 2010