Arsenic Raw Data Set 1.xlsx

This dataset consists of spot urinary total weight arsenic measurements from 5,553 samples collected for analyzing arsenic exposure levels. The dataset was used to develop and validate a novel Variable Power Functional Creatinine Correction (V-PFCRC) method, which addresses the limitations of traditional creatinine correction in adjusting for urinary dilution variability.
The Arsenic Raw Data Set 1, a crucial component of the current research project, supports the derivation of analyte-specific coefficients (c and d) used in the V-PFCRC formulas. It contains critical variables such as creatinine concentration (CRN), uncorrected arsenic concentrations (uAsUC), and sex-specific data. This dataset was instrumental in demonstrating the superior performance of V-PFCRC in normalizing urinary arsenic concentrations to a standardized CRN of 1 g/L compared to conventional correction methods.
The data were part of a more extensive study in which environmental and epidemiological research exposure assessments measured the performance of V-PFCRC across different biomarkers, including other metals and iodine. Results show a significant improvement in reducing residual CRN bias and enhancing correlations with blood arsenic levels, thus improving the accuracy of environmental and epidemiological research exposure assessments.