Enzymes used in the synthesis of DPM.
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aAbbreviations: ACS, acetyl-CoA synthetase; ACT, acetoacetyl-CoA thiolase; HMGS2, HMG-CoA synthase; ThRed, acetoacetyl-CoA thiolase/HMG-CoA reductase (dual-function enzyme); HMGR, HMG-CoA reductase; MVK, mevalonate kinase; PMK, phosphomevalonate kinase; PK, pyruvate kinase; MK, myokinase; PPiase, inorganic pyrophosphatase.
bObtained from commercial sources.
cExpressed in E. coli and purified.
dStandard errors are <5% in all cases (see Materials and Methods).
eParameters taken from literature (MK [77], [78], PPiase [79], [80]).
创建时间：
2014-08-25
