Global transcriptional profiling of Staphylococcus aureus treated with eugenol. Staphylococcus aureus

Staphylococcus aureus (S. aureus) is an important human and animal pathogen, multiply resistant strains are increasingly widespread, new agents are needed for the treatment of S. aureus. eugenol, a natural plant product, has potent antimicrobial activity against S. aureus. We employed Affymetrix Staphylococcus aureus GeneChipsTM arrays to investigate the global transcriptional profiling of Staphylococcus aureus ATCC25923 treated with eugenol. Keywords: gene expression array-based, count Overall design: Staphylococcus aureus cells were exposed for 45 minutes to eugenol at concentration of 250µg/ml (1/2× MIC), 2 samples including 1 control samples are analyzed.