Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages. Complete Bypass of Restriction Systems for Major Staphylococcus aureus Lineages
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接：
https://www.ncbi.nlm.nih.gov/bioproject/PRJEB10032
下载链接
链接失效反馈官方服务：
资源简介：
Staphylococcus aureus is a prominent global nosocomial and community-acquired bacterial pathogen. A strong restriction barrier presents a major hurdle for the introduction of recombinant DNA into clinical isolates of S. aureus. Here, we describe the construction and characterization of the IMXXB series of Escherichia coli strains that mimic the type I adenine methylation profiles of S. aureus clonal complexes 1, 8, 30, and ST93. The IMXXB strains enable direct, high-efficiency transformation and streamlined genetic manipulation of major S. aureus lineages.
创建时间：
2015-09-29
