Cipacinoids A–D, Four Limonoids with Spirocyclic Skeletons from <i>Cipadessa cinerascens</i>
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Four limonoids, cipacinoids A–D (1–4), with spirocyclic skeletons were isolated from Cipadessa cinerascens. It is particularly notable that compounds 1–3 had a 17S-configuration for the first time in the limonoid family. Their structures with absolute configurations were assigned by spectroscopic data, X-ray crystallography, and CD analysis. Compound 1 showed moderate protein tyrosine phosphatase 1B (PTP1B) inhibition.
创建时间：
2016-02-04
