List of main metabolites found in urine over a 33-day study period in NMRI female mice.

The arrows show whether the metabolic change, associated with an E. caproni infection, is significantly increased (��) or decreased (��) in infected mice compared to non-infected control mice and the numbers, next to the arrows indicate the day of maximum significance. The p-values for the changing metabolites were assessed using a non-parametric 1-way analysis of variance (Mann-Whitney U) test in MATLAB, based on the integrals of the selected peaks and were all in the range of 0.001 to 0.05.