Global gene expression analysis of MGAS10870 serotype of Group A Streptococcus (Streptococcus pyogenes/GAS) in the absence or presence of 125µg/ml human calprotectin protein

The goal was to perform global transcriptome analysis on MGAS10870 serotype to investigate and compare the gene alterations of WT grown in the presence of 125µg/ml human calprotectin protein to WT grown in the absence of 125µg/ml human calprotectin protein Overall design: There were 2 strains analyzed, each in duplicate replicates: 1) WT GAS grown to late exponential growth phase in the absence of 125µg/ml human calprotectin protein; 2) WT GAS grown to late exponential growth phase in the presence of 125µg/ml human calprotectin protein