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Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(3,5-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine

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Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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Staphylococcus aureus dihydrofolate reductase complexed with NADPH and 2,4-Diamino-5-[3-(3-methoxy-5-(3,5-dimethylphenyl)phenyl)but-1-ynyl]-6-methylpyrimidine Descriptor: 5-[(3R)-3-(5-methoxy-3',5'-dimethylbiphenyl-3-yl)but-1-yn-1-yl]-6-methylpyrimidine-2,4-diamine, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Trimethoprim-sensitive dihydrofolate reductase Authors: Anderson, A.C, Frey, K.M, Liu, J, Lombardo, M.N. Deposit date: 2008-10-25 Release date: 2009-10-06 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Crystallographic Complexes of Wildtype and Mutant MRSA DHFR Reveal Interactions for Lead Design To be Published
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2008-10-25
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