Enantioselective Rhodium-Catalyzed Synthesis of α-Chloromethylene-γ-Butyrolactams from N-Allylic Alkynamides
收藏Figshare2016-02-20 更新2026-04-29 收录
下载链接：
https://figshare.com/articles/dataset/Enantioselective_Rhodium_Catalyzed_Synthesis_of_Chloromethylene_Butyrolactams_from_i_N_i_Allylic_Alkynamides/2499784
下载链接
链接失效反馈官方服务：
资源简介：
The first enantioselective cycloisomerization with intramolecular halogen migration of various 1,6-enynes promoted by a cationic Rh-Synphos catalyst is reported. This method provides an efficient route to enantiomerically enriched γ-butyrolactam derivatives, which are important core scaffolds found in numerous natural products and biologically active molecules. Good yields and enantiomeric excesses up to 96% are achieved.
创建时间：
2016-02-20
