Relative volume of mitochondria in TK2+/+ and TK2−/− mice.

A stereological method was used to determine the volume density of the mitochondria in the cytoplasm from digital electron images taken by a Morada camera. Three different animals were analysed for each genotype and age. For each animal 9 randomly taken images from two different sections (18 images/animal) were counted making a total of 54 images/group. The P-value for statistical comparison (two-tailed unpaired Student’s t-test) between TK2+/+ and TK2−/− of the same age is shown, *p≤0.05.