Compensation of the effect of isoleucine to alanine mutation by designed inhibition in the InhA enzyme
收藏Protein Data Bank Japan2023-09-27 更新2026-03-21 收录
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Compensation of the effect of isoleucine to alanine mutation by designed inhibition in the InhA enzyme Descriptor: 2-(2-methylphenoxy)-5-[(4-phenyl-1H-1,2,3-triazol-1-yl)methyl]phenol, Enoyl-[acyl-carrier-protein] reductase [NADH], NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Li, H.-J, Lai, C.-T, Pan, P, Yu, W, Shah, S, Bommineni, G.R, Perrone, V, Garcia-Diaz, M, Tonge, P.J, Simmerling, C. Deposit date: 2015-07-21 Release date: 2015-08-12 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (3.409 Å) Cite: Rational Modulation of the Induced-Fit Conformational Change for Slow-Onset Inhibition in Mycobacterium tuberculosis InhA. Biochemistry, 54, 2015
创建时间：
2015-07-21
