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Simultaneous Pathway Activity Inference and Global Gene Expression Analysis Using RNA Sequencing

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Mendeley Data2016-05-05 更新2026-04-09 收录
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Data accompanied with the paper "Simultaneous Pathway Activity Inference and Global Gene Expression Analysis Using RNA Sequencing" The data is generated using TF-seq experimental technique that measures binding activity of more than 40 different transcription factors in parallel. It covers three experiments: * Stimulation of wild-type and Myd88 knockout BMDMs with 12 different pathogen associated molecular patterns (PAMPs) * Small molecule screen on BMDMs * Dose-response experiment using Halofuginone on BMDMs, with and without LPS stimulation The data consists of : * fastq files * associated well and reporter tags * counts of all reads, RNA and DNA UMIs * script we used to convert fastq files to count matrices
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2016-05-05
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