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Unexpected Formation of Tetrasubstituted 2,3-Dihydrofurans from the Reactions of β-Keto Polyfluoroalkanesulfones with Aldehydes

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Unexpected_Formation_of_Tetrasubstituted_2_3_Dihydrofurans_from_the_Reactions_of_Keto_Polyfluoroalkanesulfones_with_Aldehydes/3324757
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Catalyzed by piperidine, the reactions of β-keto polyfluoroalkanesulfones with aromatic aldehydes afforded the unexpected tetrasubstituted 2,3-dihydrofurans in good yields, probably proceeding through the normal Knoevenagel condensation products. This reaction provided an efficient and novel method for the stereoselective synthesis of fluorine-containing tetrasubstituted trans-2,3-dihydrofurans.
创建时间:
2016-05-06
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