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Crystal Structure of Multi-drug Resistant HIV-1 Protease PR-S17 in Complex with Darunavir

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal Structure of Multi-drug Resistant HIV-1 Protease PR-S17 in Complex with Darunavir Descriptor: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, Protease Authors: Agniswamy, J, Weber, I.T. Deposit date: 2016-08-24 Release date: 2017-01-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.5 Å) Cite: Structural Studies of a Rationally Selected Multi-Drug Resistant HIV-1 Protease Reveal Synergistic Effect of Distal Mutations on Flap Dynamics. PLoS ONE, 11, 2016
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2016-08-24
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