首页/数据集/Small molecule-induced epigenomic reprogramming of APL blasts leading to antiviral-like response and c-MYC downregulation

Small molecule-induced epigenomic reprogramming of APL blasts leading to antiviral-like response and c-MYC downregulation

NIAID Data Ecosystem2026-05-01 收录

表观遗传药物干预

急性白血病治疗

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE205346 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2023-08-10

神经病理机制

表观遗传药物干预

Histone deacetylase inhibitors (HDACIs) interfere with the epigenetic process of histone acetylation and are known to have analgesic properties in models of chronic inflammatory pain. The aim of this

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HDAC Inhibitors Correct Frataxin Deficiency in a Friedreich Ataxia Mouse Model

弗里德赖希共济失调疾病模型

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BackgroundFriedreich ataxia, an autosomal recessive neurodegenerative and cardiac disease, is caused by abnormally low levels of frataxin, an essential mitochondrial protein. All Friedreich ataxia pat

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Inhibition of epigenetic modifiers LSD1 and HDAC1 blocks rod photoreceptor death in mouse models of Retinitis Pigmentosa.

视网膜色素变性治疗

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In retinitis pigmentosa mouse models inhibitors of histone modification enzymes LSD1and HDAC1 blocked rod degeneration, preserved vision and affected the expression of multiple genes including mainten

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Targeting Taxane-Platin Resistant Lung Cancers with JumonjiC Lysine Demethylase Inhibitors (ChIP-Seq)

化疗耐药机制

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Characterization of histone 3 lysine 4 and lysine 27 trimethylation changes upon development of taxane-platin drug resistance in NSCLC cells and evaluation of these histone modifications after treatme

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E-GEOD-56691

白血病转录组

表观遗传药物干预

Transcription profiling by high throughput sequencing of CUTLL1 cell line treated with GSKJ4

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