Genetic subclone heterogeneity of tumor-initiating cells in human colorectal cancer
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https://www.omicsdi.org/dataset/ega/EGAS00001001857
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资源简介:
A subset of tumor-initiating cells (TIC) drives colorectal cancer (CRC) progression in serial mouse xenografts. The TIC compartment itself is heterogeneous and comprises hierarchically organized long-term TIC, tumor transient amplifying cells, and delayed contributing TIC. To address the genomic heterogeneity of the CRC TIC compartment, genome-wide high-coverage whole genome sequencing was performed on patient tumors (n=3), corresponding serially passaged TIC-enriched spheres, and serial xenografts.HIPO P002EGA study EGAS00001001857
创建时间:
2017-07-26



