pH Map of cryoablated MDR2 mouse
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Mice were imaged 7 days post-cryoablation. MRI and MR Spectroscopic Imaging (MRSI) data were acquired using a 9.4T Bruker horizontal bore spectrometer. Anatomical T<sub>1</sub>-weighted images were obtained using a field of view (FOV) of 25mm x 25mm and 15 slices of 0.5 mm thickness. The MRSI datasets were reconstructed to a 19×15×25 matrix, corresponding to a 1mm³ isotropic voxel resolution. The pH<sub>e</sub> in each voxel was calculated in MATLAB (MathWorks, Inc., Natick, MA) from the <sup>1</sup>H chemical shifts δ2, δ3, and δ6 of the H2, H3, and H6 protons of TmDOTP<sup>5-</sup>, respectively, as previously described. The MRSI signals were overlaid on the T<sub>1</sub>-weighted images for anatomical localization
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figshare创建时间：
2025-12-03
