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Budding yeasts inhabit a range of environments by exploiting various metabolic traits. Insight into the evolution of orthologs, paralogs and xenologs in the yeast pan-genome can help bridge these genotypes. To understand the molecular evolution of these traits in yeasts, AYbRAH homolog database is created. Information on homolog and ortholog groups can be viewed in the AYbRAH, including functional annotations, predictions for mitochondrial localization and transmembrane domains, literature references and phylogenetic reconstructions.

出芽酵母菌通过利用多样的代谢特征,得以在多种环境中栖息。解析酵母菌泛基因组(pan-genome)中直系同源基因(ortholog)、旁系同源基因(paralog)与异同源基因(xenolog)的演化过程,有助于厘清这些基因型之间的关联。为探究酵母菌上述性状的分子演化机制,研究人员构建了AYbRAH同源基因数据库。用户可在该数据库中查询同源基因及直系同源基因簇的相关信息,具体涵盖功能注释、线粒体定位预测、跨膜结构域预测、文献引用以及系统发育重建结果等内容。

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多伦多大学
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