Mycobacterium tuberculosis Genome sequencing
收藏NIAID Data Ecosystem2026-05-10 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/SRP620518
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资源简介：
The application of pan-genomics in understanding Mycobacterium tuberculosis complex (MTBC) transmission remains understudied, particularly in high-burden settings such as China. We constructed an MTBC pan-genome (MTB_pan) using 307 complete genomes representing all eight lineages. Core and accessory genomes were analyzed, lineage-associated genes were identified, and functional annotations were assessed using Pfam domains. Transmission dynamics were evaluated by comparing pan-genome- and H37Rv-based approaches for isolates collected from China, focusing on alignment rates, clustering efficiency, and single-nucleotide polymorphism (SNP) distances.
创建时间：
2025-09-26
