Interleukin-1 signaling is involved in local self-renewal and maintenance of microglia

ChEBI2015-07-15 更新2026-07-12 收录

神经免疫学

小胶质细胞

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-68376 数据链接链接失效反馈

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Interleukin-1 signaling is involved in local self-renewal and maintenance of microglia

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2015-07-15

RNA sequencing microglia depletion model

神经免疫学

RNA测序分析

We developed an experimental model system in mice, in which microglia can be depleted selectively and temporarily from the prefrontal cortex (PFC) during a defined window of adolescence (6 weeks of ag

NIAID Data Ecosystem120

Additional file 1: of Development and validation of a simplified method to generate human microglia from pluripotent stem cells

干细胞分化

小胶质细胞

Figure S1. FACS and MACS sorted HPCs differentiate into equivalent microglia as unsorted HPCs. Hierarchical clustering of all iPSmicroglia 2.0 samples show that MACS (fuchsia) and FACS (purple) sortin

DataCite Commons2020-08-27 更新70

Additional file 10: of Identification and therapeutic modulation of a pro-inflammatory subset of disease-associated-microglia in Alzheimer’s disease

神经免疫学

单细胞转录组学

3D viSNE representation of microglial modules: DAM (Red) and Homeostatic (Black) genes identified by single-cell RNAseq mapped to WGCNA modules. (HTML 3818 kb)

Figshare2018-05-22 更新50

Next Generation Sequencing Facilitates Single Cell Analysis of Wild Type and Monocyte-Depleted Brain Transcriptomes

单细胞转录组学

神经免疫学

Methods: Cells isolated from the whole brains of naive wild type, infected wild type, and infected CCR2-DTR mice were sort-purified on live CD45hi cells from five biological replicates and pooled. Sor

NIAID Data Ecosystem70

Table_2_Peripheral Humoral Immune Response Is Associated With the Non-motor Symptoms of Parkinson’s Disease.DOCX

神经免疫学

帕金森病运动症状

BackgroundNon-motor symptoms are common in Parkinson’s disease (PD) and can even be used as part of the supportive criteria for diagnosis. Chronic inflammation is involved in every stage of PD. Disord

NIAID Data Ecosystem60

Interleukin-1 signaling is involved in local self-renewal and maintenance of microglia

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