Transcriptomics and chromatin accessibility analysis of MLL-AF9 early responses in mouse bone marrow cells
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https://www.ncbi.nlm.nih.gov/sra/SRP166850
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资源简介：
We investigated early changes of gene expressions and chromatin accessibilities in hematopoietic stem and progenitor cells (HSPCs) in response to MLL-AF9 oncogene expressions. Using RNA-Seq and ATAC-Seq, we analyzed HSPCs briefly exposed to MLL-AF9 for one or two days. Such analysis addressed the initial changes during malignant transformation, and provided insights into the primary functions of MLL-AF9 oncogene. Overall design: Early cellular responses to MLL-AF9 oncogene expression were determined using RNA-Seq and ATAC-Seq of HSPCs exposed to MLL-AF9 for one or two days. Freshly isolated HSPCs and HSPCs cultured without MLL-AF9 expression were used as controls, in duplicates.
创建时间：
2020-01-01
