Summary of case series using biological agents in GCA.

Three studies (Seitz et. al, 2011 [19], Salvarani et. al, 2012 [21] and Unizony et. al, 2012 [17]) also appear in Table 3 with TAA patients. Abbreviations: TCZ (tocilizumab), monoRx (monotherapy), IFX (infliximab), CRP (C-reactive protein), NR (not reported), N/A (not applicable), F/U (followup).* In these studies, remission was defined using clinical, biochemical and the absence of new radiographic findings.** In these studies, F/U was> 6 mo while patients were in remission.*** Quality Assessment was conducted as follows: Cases series: pts enrolled consecutively or randomly vs hand-picked? Did> 90% of the pts enrolled get analyzed? Was a standardized approach used to assess remission (clinical/biochemical/radiographic). Study quality also reflects risk of bias.Summary of case series using biological agents in GCA.