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ROR gamma in complex with SCR2 and compound 3

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Protein Data Bank Japan2024-04-03 更新2026-03-21 收录
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ROR gamma in complex with SCR2 and compound 3 Descriptor: 1-[(2-chlorophenyl)methyl]-N-{[4-(methylsulfonyl)phenyl]methyl}-4',5'-dihydrospiro[piperidine-4,7'-thieno[2,3-c]pyran]-2'-carboxamide, GLYCEROL, Nuclear receptor ROR-gamma, ... Authors: Durbin, J.D, Guo, S.Y, Stout, S.L, Clawson, D.K. Deposit date: 2020-10-06 Release date: 2021-04-21 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Defining Target Engagement Required for Efficacy In Vivo at the Retinoic Acid Receptor-Related Orphan Receptor C2 (ROR gamma t). J.Med.Chem., 64, 2021
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2020-10-06
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