Tankyrases are multifunctional poly(adenosine diphosphate-ribose) polymerases that regulate diverse biological processes including telomere maintenance and cellular signaling. These processes are oft

NIAID Data Ecosystem90

Identification of Selective Small Molecule Inhibitors of the Nucleotide-Binding Oligomerization Domain 1 (NOD1) Signaling Pathway

NOD1信号通路抑制

小分子药物

NOD1 is an intracellular pattern recognition receptor that recognizes diaminopimelic acid (DAP), a peptidoglycan component in gram negative bacteria. Upon ligand binding, NOD1 assembles with receptor-

Figshare2016-01-18 更新30

Additional file 6 of YBX1 regulation of alveolar type II epithelial cells in idiopathic pulmonary fibrosis: mechanistic insights and small-molecule drug screening

特发性肺纤维化机制

小分子药物

Supplementary Material 6: Supplementary Table 5

DataCite Commons2025-11-19 更新110

BindingDB Entry 50018444: Progress in PD-1/PD-L1 pathway inhibitors: From biomacromolecules to small molecules.

免疫检查点抑制剂

小分子药物

Small molecule binding data for protein Platelet-derived growth factor receptor alpha/beta, Programmed cell death 1 ligand 1, and Programmed cell death 1 ligand 2, Uniprot P05622, P26618, Q9BQ51, Q9EP

DataCite Commons2024-04-26 更新30

2023 Approved small-molecule drugs

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