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Multi-omics profiling of mouse myocardial infarction

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NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP269222
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资源简介:
Myocardial infarction (MI), the most severe manifestation of coronary artery disease, is a multifactorial pathophysiologic process. Here, we constructed a MI mouse model through ligation of the proximal left anterior descending coronary artery. Then we detected and analysed multi-omics (transcriptome and proteome) at different time points (Control, 10 mininte, 1 hour, 6 hour, 24 hour and 72 hour) after MI. Immune-related pathway, pyroptosis pathway, and autophagy pathway r were significantly increased after MI. Overall design: RNA-seq analysis of mouse myocardial infarction at different time points (Control, 10 mininte, 1 hour, 6 hour, 24 hour and 72 hour) after MI.
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2022-05-16
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