Structure of CHK1 10-pt. mutant complex with LRRK2 inhibitor 22
收藏Protein Data Bank Japan2023-10-18 更新2026-04-19 收录
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Structure of CHK1 10-pt. mutant complex with LRRK2 inhibitor 22 Descriptor: (3R,4R)-4-{(3S,4S)-4-[6-chloro-2-({5-chloro-1-[(1R)-2,2-difluorocyclopropyl]-1H-pyrazol-4-yl}amino)quinazolin-7-yl]-3-fluoropiperidin-1-yl}oxolan-3-ol, Serine/threonine-protein kinase Chk1 Authors: Palte, R.L. Deposit date: 2021-11-17 Release date: 2022-01-12 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.119 Å) Cite: Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors. J.Med.Chem., 65, 2022
创建时间：
2021-11-17
