Pseudomonas isolates that display anti-microsporidia activity against N. parisii.

The goal of this work was to uncover how the native C. elegans microbiome impacts host health upon infection with the obligate intracellular microsporidian parasite N. parisii. A panel of 53 wild isolates of pseudomonas was screened and 6 of the strains with the highest activity and greatest phylogenetic diversity were selected for whole genome sequencing. The goal was to use the whole genome sequences to uncover what diversity of natural compounds they produce, to identify candidate molecules that target N. parisii.