Factor H binds to C3b
收藏reactome.org2025-01-15 收录
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Factor H (CFH) regulates the alternative pathway C3 convertase C3bBb and its C3b component both in plasma and at host cell surfaces. FH binds to plasma C3b, making it unavailable, and acts as a cofactor for the factor I-mediated proteolytic inactivation of C3b to iC3b.
因子H（CFH）调控替代途径中的C3bBb转化酶及其C3b组分，无论是在血浆中还是在宿主细胞表面。FH与血浆中的C3b结合，使其不可利用，并作为因子I介导的C3b蛋白水解失活的辅助因子。
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