Vascular smooth muscle cell: control vs. exposed to nicotine. Homo sapiens

NIAID Data Ecosystem2026-03-08 收录

尼古丁毒性

平滑肌细胞转录调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA243079 数据链接链接失效反馈

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资源简介：

Transcriptional profiling of human aortic smooth muscle cells (HSMCs) comparing exposed with nicotine or not. Overall design: Two-condition experiment, control vs. treated HSMCs by nicotine.

创建时间：

2014-03-31

Data from: Effects of nicotine on corneal wound healing following acute alkali burn

角膜伤口愈合

尼古丁毒性

Epidemiological studies have indicated that smoking is a pivotal risk factor for the progression of several chronic diseases. Nicotine, the addictive component of cigarettes, has powerful pathophysiol

DataONE2017-06-30 更新80

Transciptomic analysis of human aortic smooth muscle cells (HASMCs) with BAF60a knockdown

平滑肌细胞转录调控

基因功能缺失分析

We used NGS-derived transcriptome profiling (RNA-seq) to compare the transcriptional difference between human aortic smooth muscle cells (HASMCs) transfected with 30nM siRNA targeting BAF60a (siBAF60a

NIAID Data Ecosystem30

Effects of siRNA gene silencing on transcriptional responses of human synovial fibroblasts to TNF and IL-17A (RNA-seq Data 2). Effects of siRNA gene silencing on transcriptional responses of human synovial fibroblasts to TNF and IL-17A (RNA-seq Data 2)

平滑肌细胞转录调控

炎症反应基因

TNF and IL-17A synergistic effects on gene expression after silencing CUX1, LIFR, STAT3, STAT4, ELF3 Overall design: Human fibroblasts were transfected with siRNAs and then stimulated with TNF or TNF

NIAID Data Ecosystem20

Data_Sheet_1_Postnatal Smad3 Inactivation in Murine Smooth Muscle Cells Elicits a Temporally and Regionally Distinct Transcriptional Response.PDF

主动脉瘤分子机制

平滑肌细胞转录调控

Heterozygous, loss of function mutations in positive regulators of the Transforming Growth Factor-β (TGF-β) pathway cause hereditary forms of thoracic aortic aneurysm. It is unclear whether and how th

NIAID Data Ecosystem40

Paternal nicotine enhances fear memory, reduces nicotine administration and alters hippocampal genetic and neural function in offspring [Bisulfite-seq]. Paternal nicotine enhances fear memory, reduces nicotine administration and alters hippocampal genetic and neural function in offspring [Bisulfite-seq]

跨代表观遗传

尼古丁毒性

We tested the effects of chronic paternal nicotine exposure in C57BL6/J mice on hippocampal DNA methylation in F1 offspring. Overall design: Examination of differential DNA methylation in the hippocam

NIAID Data Ecosystem20

Vascular smooth muscle cell: control vs. exposed to nicotine. Homo sapiens

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