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Expression data from Hap1 parental control and Baz2B-KO cell lines

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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE218705
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Baz2B protein was shown to form a chromatin remodelig complex mit Snf2H or Snf2L catalytic subunits. It is known that chromatin remodeling proteins regulate diffferent DNA-templated processes, therefore we wanted to know whether Baz2B plays a role in transcription regulation. We used microarrays to detail the global expression of transcripts in Hap1 parental cell line and compare them to Baz2B-KO. We found up- and down-regulated trasncripts that could be associated with the decreased cellular proliferation in Baz2B-KO cell line Baz2B-KO (n=2) against parental Hap1 cells (ctrl, n=2)
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2023-11-28
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