Structure of PLK1 kinase domain in complex with a benzolactam-derived inhibitor
收藏Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
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Structure of PLK1 kinase domain in complex with a benzolactam-derived inhibitor Descriptor: 9-chloro-2-({5-[3-(dimethylamino)propyl]-2-methylpyridin-3-yl}amino)-5,7-dihydro-6H-pyrimido[5,4-d][1]benzazepine-6-thi one, Serine/threonine-protein kinase PLK1, ZINC ION Authors: Sintchak, M.D. Deposit date: 2011-08-18 Release date: 2011-11-23 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905). J.Med.Chem., 55, 2012
创建时间：
2011-08-18
