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An atypical parvovirus driving chronic tubulointerstitial nephropathy and kidney fibrosis

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NIAID Data Ecosystem2026-03-11 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE117710
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We have performed RNA sequencing on kidneys from inclusion body nephropathy-affected mice and compared the data to healthy, uninfected controls. Using a metagenomics approach, we report the identification of the disease causing agent as an atypical virus, mouse kidney parvovirus (MKPV), belonging to a divergent genus of the Parvoviridae. The RNA sequencing also enabled us to assess the host response to MKPV-infection. Examination of whole kidney transcriptomes from 2 sick and 2 healthy mice. BioProject ID: PRJNA482006. SRA accession no: SRP154484
创建时间:
2019-03-19
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