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RNA-seq analysis of WT and NCOR1f/f,Cd4Cre naive CD4+ T cells

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NIAID Data Ecosystem2026-03-11 收录
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The differentiation of naïve CD4+ T cells into T helper (Th) subsets is key for a functional immune response and has to be tightly controlled by transcriptional and epigenetic processes. However, the function of cofactors that connect gene-specific transcription factors with repressive chromatin-modifying enzymes in Th cells is yet unknown. Here we determined transcriptional changes in naive CD4+ T cells upon deletion of the cofactor NCOR1. mRNA expression profiles of WT and NCOR1f/f,Cd4Cre naive CD4+ T cells were generated by deep sequencing.

创建时间:
2020-04-27
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