HLA-DQB1/DQA2 lead variant locus in T2D and non-T2D strata.

A) Locus zoom plot for HLA-DQB1/DQA2 loci in T2D strata. B) Locus zoom plot for HLA-DQB1/DQA2 loci in non-T2D strata. X-axis defines the genomic position where variants +/-500 kb on either side of rs9274619—chr6:32635954:G:A (grc37) is mapped on the genome. The variants are colored based on the r2 with the lead variant and the genes are mapped based on their genomic position. Y-axis is the -log10(p-values) from the respective strata and the scale of y-axis is different between the two plots. HLA–Human Leukocyte Antigen; T2D –Type 2 Diabetes. (ZIP)