Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG056
收藏Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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Crystal Structure of the first bromodomain of human BRD4 in complex with the inhibitor JWG056 Descriptor: 2-{[3-methoxy-4-(4-methylpiperazin-1-yl)phenyl]amino}-5-methyl-11-(propan-2-yl)-5,11-dihydro-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one, Bromodomain-containing protein 4 Authors: Xu, X, Blacklow, S.C. Deposit date: 2018-02-26 Release date: 2019-03-06 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (1.47 Å) Cite: Structural and Atropisomeric Factors Governing the Selectivity of Pyrimido-benzodiazipinones as Inhibitors of Kinases and Bromodomains. Acs Chem.Biol., 13, 2018
创建时间：
2018-02-26
