Single-cell RNA sequencing identifies Endothelial derived HBEGF promoting Pancreatic Beta Cell Proliferation via EGFR-Kmt5a-H4K20me Pathway [bulk RNA-seq]

Pancreatic beta cells mass is dynamically regulated in response to increased physiological demands during pregnancy. We used RNA sequencing (RNA-seq) to analyze the diversity and character of islets cells in pancreas. RNA sequencing (RNA-seq) was applied to analyze isolated islets from mice at virgin and gestational day14.5.