Transcriptome sequencing data of tier 1 mutations.

The expression of tier1 genes was estimated using Transcriptome sequencing data. For each gene, identified by a unique Ensembl identity (ID) code, the estimation of expression was calculated using Cufflinks and reported as FPKM (number of fragments per kilobase of exon per million fragments mapped: Cufflinks FPKM). Each FPKM value was calculated with a confidence interval ranging between Low CI and High CI values. Mutated allele expression summarizes the percentage of mutated reads covering the mutation site.