Crystal structure of S. aureus FabI in complex with NADPH and kalimantacin B
收藏Protein Data Bank Japan2024-01-24 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/6tbc
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of S. aureus FabI in complex with NADPH and kalimantacin B Descriptor: (2~{E},5~{R},10~{E},12~{E},15~{S},19~{R})-20-[[(2~{R},3~{R})-3-aminocarbonyloxy-2-methyl-butanoyl]amino]-3,5,15-trimethyl-7-methylidene-19-oxidanyl-17-oxidanylidene-icosa-2,10,12-trienoic acid, Enoyl-[acyl-carrier-protein] reductase [NADPH], NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE Authors: Fage, C.D, Masschelein, J. Deposit date: 2019-11-01 Release date: 2020-04-01 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.55 Å) Cite: The Kalimantacin Polyketide Antibiotics Inhibit Fatty Acid Biosynthesis in Staphylococcus aureus by Targeting the Enoyl-Acyl Carrier Protein Binding Site of FabI. Angew.Chem.Int.Ed.Engl., 59, 2020
创建时间：
2019-11-01
