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Crystal structure of the VEGFR2 kinase domain in complex with a benzoxazole inhibitor

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Protein Data Bank Japan2024-10-16 更新2026-03-21 收录
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Crystal structure of the VEGFR2 kinase domain in complex with a benzoxazole inhibitor Descriptor: 4-({2-[(4-chloro-3-{[(2S)-1-methylpyrrolidin-2-yl]methoxy}phenyl)amino]-1,3-benzoxazol-5-yl}oxy)-N-methylpyridine-2-carboxamide, SULFATE ION, Vascular endothelial growth factor receptor 2 Authors: Whittington, D.A, Kim, J.L, Long, A.M, Rose, P, Gu, Y, Zhao, H. Deposit date: 2007-08-03 Release date: 2007-09-25 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Design, Synthesis, and Evaluation of Orally Active Benzimidazoles and Benzoxazoles as Vascular Endothelial Growth Factor-2 Receptor Tyrosine Kinase Inhibitors. J.Med.Chem., 50, 2007
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2007-08-03
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