Effects of EZH2 ablation on promoter accessibility in mouse PDAC lines derived from KrasG12D/PEC/IkkαΔPEC tumors
收藏NIAID Data Ecosystem2026-03-13 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE148335
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资源简介：
We analyzed chromatin accessibility genome wide in EZH2KO and control cells derived from PDAC tumors of KrasG12D/PEC-IkkαΔPEC PDAC model mice to gain insight how the ablation of EZH2 affects the accessibility of genes involved in PDAC tumorigenesis. ATAC-seq was performed in two established cell lines, EZH2KO-UN-KC-6141, and control-UN-KC-6141. UN-KC-6141 is a line derived from PDAC tumors from KrasG12D/PEC-IkkαΔPEC mice.
创建时间：
2021-12-31
